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How Much Money Does The United States Spend On Biodefense

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Terrorism involving biological agents

Bioterrorism is terrorism involving the intentional release or dissemination of biological agents. These agents are bacteria, viruses, insects, fungi or toxins, and may be in a naturally occurring or a homo-modified form, in much the same way equally in biological warfare. Further, mod agribusiness is vulnerable to anti-agricultural attacks past terrorists, and such attacks can seriously damage economy as well equally consumer confidence.[1] The latter destructive activeness is called agrobioterrorism and is a subtype of agro-terrorism.[two]

Definition [edit]

Bioterrorism is the deliberate release of viruses, bacteria, toxins or other harmful agents to cause illness or death in people, animals, or plants.[3] These agents are typically institute in nature, but could exist mutated or contradistinct to increase their ability to cause disease, make them resistant to current medicines, or to increase their ability to exist spread into the environment. Biological agents tin can exist spread through the air, water, or in food. Biological agents are attractive to terrorists considering they are extremely hard to detect and do not cause disease for several hours to several days. Some bioterrorism agents, similar the smallpox virus, tin exist spread from person to person and some, like anthrax, cannot.[4] [v] Bioterrorism may be favored because biological agents are relatively easy and cheap to obtain, can be easily disseminated, and can cause widespread fear and panic across the bodily physical damage.[6] War machine leaders, nevertheless, accept learned that, as a military asset, bioterrorism has some important limitations; information technology is difficult to use a bioweapon in a mode that only affects the enemy and not friendly forces. A biological weapon is useful to terrorists mainly equally a method of creating mass panic and disruption to a state or a country. However, technologists such as Pecker Joy accept warned of the potential power which genetic engineering might place in the hands of future bio-terrorists.[7]

The employ of agents that do non cause harm to humans, but disrupt the economic system, take likewise been discussed.[8] One such pathogen is the foot-and-mouth disease (FMD) virus, which is capable of causing widespread economic damage and public business (as witnessed in the 2001 and 2007 FMD outbreaks in the UK), while having almost no capacity to infect humans.

History [edit]

By the time World War I began, attempts to use anthrax were directed at creature populations. This generally proved to be ineffective.

Soon after the starting time of World War I, Frg launched a biological sabotage campaign in the The states, Russia, Romania, and France.[ix] At that time, Anton Dilger lived in Deutschland, but in 1915 he was sent to the United States carrying cultures of glanders, a virulent disease of horses and mules. Dilger gear up upwardly a laboratory in his home in Chevy Chase, Maryland. He used stevedores working the docks in Baltimore to infect horses with glanders while they were waiting to be shipped to Britain. Dilger was nether suspicion as being a German agent, simply was never arrested. Dilger eventually fled to Madrid, Spain, where he died during the Influenza Pandemic of 1918.[ten] In 1916, the Russians arrested a German agent with like intentions. Germany and its allies infected French cavalry horses and many of Russian federation's mules and horses on the Eastern Front. These actions hindered artillery and troop movements, equally well as supply convoys.[9]

In 1972, police in Chicago arrested two higher students, Allen Schwander and Stephen Pera, who had planned to poison the metropolis'southward water supply with typhoid and other bacteria. Schwander had founded a terrorist grouping, "R.I.S.Eastward.", while Pera collected and grew cultures from the hospital where he worked. The ii men fled to Cuba after beingness released on bail. Schwander died of natural causes in 1974, while Pera returned to the U.Southward. in 1975 and was put on probation.[11]

In 1980, the Earth Health Organization (WHO) announced the eradication of smallpox, a highly contagious and incurable disease. Although the disease has been eliminated in the wild, frozen stocks of smallpox virus are still maintained by the governments of the United States and Russia. Disastrous consequences are feared if rogue politicians or terrorists were to get hold of the smallpox strains.[ citation needed ] Since vaccination programs are at present terminated, the earth population is more susceptible to smallpox than ever before.

In Oregon in 1984, followers of the Bhagwan Shree Rajneesh attempted to control a local election by incapacitating the local population. They infected salad bars in 11 restaurants, produce in grocery stores, doorknobs, and other public domains with Salmonella typhimurium bacteria in the metropolis of The Dalles, Oregon. The attack infected 751 people with astringent food poisoning. There were no fatalities. This incident was the first known bioterrorist attack in the United States in the 20th century.[12] It was likewise the single largest bioterrorism assault on U.Southward. soil.[13]

In June 1993, the religious grouping Aum Shinrikyo released anthrax in Tokyo. Eyewitnesses reported a foul olfactory property. The attack was a failure, considering it did not infect a unmarried person. The reason for this is due to the fact that the group used the vaccine strain of the bacterium. The spores which were recovered from the site of the attack showed that they were identical to an anthrax vaccine strain that was given to animals at the time. These vaccine strains are missing the genes that cause a symptomatic response.[fourteen]

In September and October 2001, several cases of anthrax broke out in the United States, apparently deliberately acquired. Letters laced with infectious anthrax were meantime delivered to news media offices and the U.Due south Congress, alongside an ambiguously related example in Republic of chile. The letters killed five people.[fifteen]

Scenarios [edit]

There are multiple considerable scenarios, how terrorists might employ biological agents.[one] In 2000, tests conducted by various US agencies showed that indoor attacks in densely populated spaces are much more serious than outdoor attacks. Such enclosed spaces are large buildings, trains, indoor arenas, theaters, malls, tunnels and similar. Contra-measures against such scenarios are edifice compages and ventilation systems engineering. In 1993, sewage was spilled out into a river, subsequently fatigued into the h2o system and affected 400,000 people in Milwaukee, Wisconsin.[16] The illness-causing organism was cryptosporidium parvum. This human-fabricated disaster can be a template for a terrorist scenario.[1] Nevertheless, terrorist scenarios are considered more likely well-nigh the points of delivery than at the h2o sources earlier the water treatment.[1] Release of biological agents is more likely for a single edifice or a neighborhood. Counter-measures confronting this scenario include the further limitation of access to the h2o supply systems, tunnels, and infrastructure. Agronomical crop-squeegee flights might be misused equally delivery devices for biological agents equally well.[one] Counter-measures confronting this scenario are background checks of employees of ingather-dusting companies and surveillance procedures.

In the most common hoax scenario, no biological agents are employed.[17] For instance, an envelope with powder in it that says, "Y'all've just been exposed to anthrax." Such hoaxes have been shown to have a large psychological bear upon on the population.[eighteen]

Anti-agronomics attacks are considered to require relatively little expertise and applied science.[eighteen] Biological agents that set on livestock, fish, vegetation, and crops are mostly not contagious to humans and are therefore easier for attackers to handle. Fifty-fifty a few cases of infection can disrupt a state's agricultural production and exports for months, as evidenced past FMD outbreaks.

Types of agents [edit]

Under current United States law, bio-agents which have been declared by the U.S. Department of Health and Human being Services or the U.Due south. Department of Agriculture to have the "potential to pose a severe threat to public health and safety" are officially defined as "select agents." The CDC categorizes these agents (A, B or C) and administers the Select Agent Program, which regulates the laboratories which may possess, employ, or transfer select agents inside the Us. Every bit with US attempts to categorize harmful recreational drugs, designer viruses are non all the same categorized and avian H5N1 has been shown to achieve high mortality and human-advice in a laboratory setting.

Category A [edit]

These high-priority agents pose a risk to national security, can be easily transmitted and disseminated, upshot in loftier mortality, have potential major public wellness impact, may crusade public panic, or require special action for public health preparedness.

  • SARS, though non as lethal as other diseases, was apropos to scientists[19] [xx] and policymakers for its social and economic disruption potential.[21] After the global containment of the pandemic, the United States President George West. Bush stated "...A global influenza pandemic that infects millions and lasts from i to iii years could be far worse."[22]
  • Tularemia or "rabbit fever":[23] Tularemia has a very low fatality rate if treated, merely can severely incapacitate. The disease is acquired by the Francisella tularensis bacterium, and can be contracted through contact with fur, inhalation, ingestion of contaminated water or insect bites. Francisella tularensis is very infectious. A pocket-sized number of organisms (ten–50 or so) can cause illness. If F. tularensis were used as a weapon, the bacteria would likely be made airborne for exposure by inhalation. People who inhale an infectious droplets would more often than not experience severe respiratory illness, including life-threatening pneumonia and systemic infection, if they are not treated. The bacteria that cause tularemia occur widely in nature and could exist isolated and grown in quantity in a laboratory, although manufacturing an constructive aerosol weapon would crave considerable sophistication.[24]
  • Anthrax: Anthrax is a non-contagious illness caused by the spore-forming bacterium Bacillus anthracis. The ability of Anthrax to produce within small spores, or bacilli bacterium, makes it readily permeable to porous skin and tin can cause abrupt symptoms within 24 hours of exposure. The dispersal of this pathogen among densely populated areas is said to carry less than ane percent mortality charge per unit, for cutaneous exposure, to a 90 percent or higher mortality for untreated inhalational infections.[25] An anthrax vaccine does exist but requires many injections for stable use. When discovered early, anthrax can be cured by administering antibiotics (such as ciprofloxacin).[26] Its first mod incidence in biological warfare were when Scandinavian "freedom fighters" supplied by the German General Staff used anthrax with unknown results against the Purple Russian Ground forces in Republic of finland in 1916.[27] In 1993, the Aum Shinrikyo used anthrax in an unsuccessful attempt in Tokyo with nix fatalities.[fourteen] Anthrax was used in a series of attacks past a microbiologist at the US Ground forces Medical Inquiry Institute of Infection Disease on the offices of several Us Senators in late 2001. The anthrax was in a powder form and information technology was delivered by the postal service.[28] This bioterrorist assault inevitably prompted seven cases of cutaneous anthrax and eleven cases of inhalation anthrax, with v leading to deaths. Additionally, an estimated ten to 26 cases had prevented fatality through treatment supplied to over thirty,000 individuals.[29] Anthrax is one of the few biological agents that federal employees have been vaccinated for. In the United states of america an anthrax vaccine, Anthrax Vaccine Adsorbed (AVA) exists and requires five injections for stable use. Other anthrax vaccines as well exist. The strain used in the 2001 anthrax attacks was identical to the strain used past the USAMRIID.[30]
  • Smallpox:[31] Smallpox is a highly contagious virus. It is transmitted easily through the atmosphere and has a high mortality rate (20–40%). Smallpox was eradicated in the earth in the 1970s, thanks to a worldwide vaccination program.[32] However, some virus samples are nevertheless available in Russian and American laboratories. Some believe that after the plummet of the Soviet Matrimony, cultures of smallpox accept become available in other countries. Although people born pre-1970 volition have been vaccinated for smallpox under the WHO program, the effectiveness of vaccination is limited since the vaccine provides high level of immunity for but 3 to 5 years. Revaccination's protection lasts longer.[33] As a biological weapon smallpox is unsafe because of the highly contagious nature of both the infected and their pox. Also, the infrequency with which vaccines are administered among the general population since the eradication of the disease would leave virtually people unprotected in the event of an outbreak. Smallpox occurs but in humans, and has no external hosts or vectors.
  • Botulinum toxin:[34] The neurotoxin[35] Botulinum is the deadliest toxin known to man, and is produced by the bacterium Clostridium botulinum. Botulism causes decease by respiratory failure and paralysis.[36] Furthermore, the toxin is readily bachelor worldwide due to its cosmetic applications in injections.
  • Bubonic plague:[37] Plague is a disease acquired by the Yersinia pestis bacterium. Rodents are the normal host of plague, and the disease is transmitted to humans by flea bites and occasionally past aerosol in the course of pneumonic plague.[38] The disease has a history of apply in biological warfare dating dorsum many centuries, and is considered a threat due to its ease of civilisation and ability to remain in circulation among local rodents for a long menses of time. The weaponized threat comes mainly in the course of pneumonic plague (infection by inhalation)[39] It was the affliction that caused the Black Death in Medieval Europe.
  • Viral hemorrhagic fevers:[40] This includes hemorrhagic fevers caused by members of the family Filoviridae (Marburg virus and Ebola virus), and past the family Arenaviridae (for example Lassa virus and Machupo virus). Ebola virus disease, in particular, has caused high fatality rates ranging from 25 to 90% with a fifty% average. No cure currently exists, although vaccines are in development. The Soviet Union investigated the utilise of filoviruses for biological warfare, and the Aum Shinrikyo group unsuccessfully attempted to obtain cultures of Ebola virus.[41] Expiry from Ebola virus disease is unremarkably due to multiple organ failure and hypovolemic shock. Marburg virus was outset discovered in Marburg, Frg. No treatments currently exist aside from supportive care. The arenaviruses have a somewhat reduced case-fatality rate compared to disease caused by filoviruses, but are more widely distributed, importantly in key Africa and Due south America.

Category B [edit]

Category B agents are moderately piece of cake to disseminate and accept low mortality rates.

  • Brucellosis (Brucella species)[42]
  • Epsilon toxin of Clostridium perfringens
  • Food rubber threats (for case, Salmonella species, E coli O157:H7, Shigella, Staphylococcus aureus)
  • Glanders[43] (Burkholderia mallei)
  • Melioidosis (Burkholderia pseudomallei)[44] [45]
  • Psittacosis (Chlamydia psittaci)
  • Q fever (Coxiella burnetii)[46]
  • Ricin[47] toxin from Ricinus communis (castor beans)
  • Abrin toxin from Abrus precatorius (Rosary peas)
  • Staphylococcal enterotoxin B
  • Typhus (Rickettsia prowazekii)
  • Viral encephalitis (alphaviruses, for example,: Venezuelan equine encephalitis, eastern equine encephalitis, western equine encephalitis)
  • Water supply threats (for example, Vibrio cholerae,[48] Cryptosporidium parvum)

Category C [edit]

Category C agents are emerging pathogens that might exist engineered for mass broadcasting because of their availability, ease of production and dissemination, high mortality rate, or ability to cause a major health impact.

  • Nipah virus
  • Hantavirus

Planning and response [edit]

Planning may involve the development of biological identification systems. Until recently in the United States, near biological defence strategies have been geared to protecting soldiers on the battleground rather than ordinary people in cities. Fiscal cutbacks accept limited the tracking of disease outbreaks. Some outbreaks, such as nutrient poisoning due to E. coli or Salmonella, could exist of either natural or deliberate origin.

Preparedness [edit]

Export controls on biological agents are not practical uniformly, providing terrorists a route for acquisition.[49] Laboratories are working on advanced detection systems to provide early warning, place contaminated areas and populations at run a risk, and to facilitate prompt treatment.[50] Methods for predicting the employ of biological agents in urban areas as well every bit assessing the expanse for the hazards associated with a biological attack are being established in major cities. In improver, forensic technologies are working on identifying biological agents, their geographical origins and/or their initial source. Efforts include decontamination technologies to restore facilities without causing additional environmental concerns.

Early on detection and rapid response to bioterrorism depend on close cooperation between public health authorities and constabulary enforcement; however, such cooperation is lacking. National detection avails and vaccine stockpiles are not useful if local and state officials practice non take access to them.[51]

Aspects of protection confronting bioterrorism in the Usa include:

  • Detection and resilience strategies in combating bioterrorism. This occurs primarily through the efforts of the Office of Health Affairs (OHA), a part of the Department of Homeland Security (DHS), whose role is to fix for an emergency situation that impacts the wellness of the American populace. Detection has two principal technological factors. First in that location is OHA's BioWatch programme in which drove devices are disseminated to 30 high risk areas throughout the state to find the presence of aerosolized biological agents before symptoms present in patients.[52] This is significant primarily because it allows a more proactive response to a disease outbreak rather than the more passive handling of the past.
  • Implementation of the Generation-three automatic detection organization. This advocacy is meaning simply because it enables activity to be taken in four to six hours due to its automatic response system, whereas the previous system required aerosol detectors to be manually transported to laboratories.[52] Resilience is a multifaceted issue besides, every bit addressed by OHA. I way in which this is ensured is through exercises that plant preparedness; programs like the Anthrax Response Practice Series be to ensure that, regardless of the incident, all emergency personnel will be enlightened of the role they must fill up.[52] Moreover, by providing information and teaching to public leaders, emergency medical services and all employees of the DHS, OHS suggests it can significantly decrease the bear on of bioterrorism.[52]
  • Enhancing the technological capabilities of first responders is accomplished through numerous strategies. The first of these strategies was developed past the Scientific discipline and Technology Advisers (S&T) of DHS to ensure that the danger of suspicious powders could be effectively assessed, (as many dangerous biological agents such as anthrax exist as a white pulverisation). By testing the accuracy and specificity of commercially available systems used past first responders, the hope is that all biologically harmful powders can be rendered ineffective.[53]
  • Enhanced equipment for first responders. One recent advancement is the commercialization of a new form of Tyvex™ armor which protects first responders and patients from chemical and biological contaminants. There has as well been a new generation of Self-Independent Breathing Apparatuses (SCBA) which has been recently fabricated more robust against bioterrorism agents. All of these technologies combine to course what seems like a relatively strong deterrent to bioterrorism. However, New York City every bit an entity has numerous organizations and strategies that finer serve to deter and answer to bioterrorism equally it comes. From here the logical progression is into the realm of New York Metropolis's specific strategies to forestall bioterrorism.[53]
  • Excelsior Challenge. In the 2d week of September 2016, the land of New York held a large emergency response preparation exercise called the Excelsior Challenge, with over 100 emergency responders participating. According to WKTV, "This is the fourth twelvemonth of the Excelsior Challenge, a training practice designed for law and first responders to get familiar with techniques and practices should a real incident occur."[54] The event was held over three days and hosted by the State Preparedness Preparation Center in Oriskany, New York. Participants included bomb squads, canine handlers, tactical team officers and emergency medical services.[55] In an interview with Homeland Preparedness News, Bob Stallman, assistant manager at the New York State Preparedness Training Middle, said, "We're constantly seeing what's happening around the world and we tailor our training courses and events for those types of real-world events." For the first time, the 2016 training programme implemented New York's new electronic arrangement. The system, called NY Responds, electronically connects every canton in New York to aid in disaster response and recovery. As a result, "counties accept admission to a new engineering science known equally Mutualink, which improves interoperability by integrating telephone, radio, video, and file-sharing into 1 application to permit local emergency staff to share real-time data with the country and other counties."[55] The State Preparedness Training Center in Oriskany was designed by the State Sectionalization of Homeland Security, and Emergency Services (DHSES) in 2006. It toll $42 1000000 to construct on over 1100 acres and is available for training 360 days a twelvemonth.[56] Students from SUNY Albany's College of Emergency Preparedness, Homeland Security and Cybersecurity, were able to participate in this yr's practice and learn how "DHSES supports law enforcement specialty teams."[55]
  • Project BioShield. The accrual of vaccines and treatments for potential biological threats, also known as medical countermeasures has been an important aspect in preparing for a potential bioterrorist attack; this took the form of a program offset in 2004, referred to every bit Projection BioShield.[57] The significance of this program should not be overlooked as "there is currently enough smallpox vaccine to inoculate every United States citizen… and a multifariousness of therapeutic drugs to treat the infected."[57] The Department of Defense also has a variety of laboratories currently working to increase the quantity and efficacy of countermeasures that comprise the national stockpile.[58] Efforts have likewise been taken to ensure that these medical countermeasures can be disseminated effectively in the event of a bioterrorist attack. The National Clan of Concatenation Drug Stores championed this cause by encouraging the participation of the private sector in improving the distribution of such countermeasures if required.[58]

On a CNN news broadcast in 2011, the CNN chief medical correspondent, Dr. Sanjay Gupta, weighed in on the American government's recent approach to bioterrorist threats. He explains how, even though the United States would be better fending off bioterrorist attacks now than they would exist a decade ago, the amount of money available to fight bioterrorism over the terminal three years has begun to decrease. Looking at a detailed study that examined the funding decrease for bioterrorism in fifty-one American cities, Dr. Gupta stated that the cities "wouldn't be able to distribute vaccines as well" and "wouldn't exist able to runway viruses." He as well said that film portrayals of global pandemics, such as Contagion, were actually quite possible and may occur in the The states under the correct atmospheric condition.[59]

A news broadcast past MSNBC in 2010 also stressed the low levels of bioterrorism preparedness in the The states. The broadcast stated that a bipartisan report gave the Obama administration a failing grade for its efforts to answer to a bioterrorist assault. The news broadcast invited the old New York City police commissioner, Howard Safir, to explain how the government would fare in combating such an assault. He said how "biological and chemical weapons are likely and relatively easy to disperse." Furthermore, Safir thought that efficiency in bioterrorism preparedness is not necessarily a question of money, only is instead dependent on putting resources in the right places. The broadcast suggested that the nation was not set for something more serious.[lx]

In a September 2016 interview conducted past Homeland Preparedness News, Daniel Gerstein, a senior policy researcher for the RAND Corporation, stresses the importance in preparing for potential bioterrorist attacks on the nation. He implored the U.S. government to take the proper and necessary actions to implement a strategic program of activity to relieve as many lives equally possible and to safeguard against potential anarchy and confusion. He believes that because there take been no meaning instances of bioterrorism since the anthrax attacks in 2001, the government has allowed itself to become conceited making the country that much more vulnerable to unsuspecting attacks, thereby further endangering the lives of U.S. citizens.[61]

Gerstein formerly served in the Science and Applied science Directorate of the Department of Homeland Security from 2011 to 2014. He claims there has non been a serious plan of action since 2004 during George W. Bush's presidency, in which he issued a Homeland Security directive delegating responsibilities amidst various federal agencies. He too stated that the blatant mishandling of the Ebola virus outbreak in 2014 attested to the regime's lack of training. This by May, legislation that would create a national defence strategy was introduced in the Senate, coinciding with the timing of ISIS-affiliated terrorist groups get closer to weaponizing biological agents. In May, 2016, Kenyan officials apprehended two members of an Islamic extremist group in motility to gear up off a biological bomb containing anthrax. Mohammed Abdi Ali, the believed leader of the group, who was a medical intern, was arrested along with his wife, a medical student. The two were caught just earlier carrying out their programme.[62] The Bluish Ribbon Study Panel on Biodefense, which comprises a group of experts on national security and government officials, in which Gerstein had previously testified to, submitted its National Blueprint for Biodefense to Congress in October 2015 listing their recommendations for devising an effective plan.[61]

Neb Gates said in a February 18, 2017 Business organization Insider op-ed (published near the time of his Munich Security Conference speech) that it is possible for an airborne pathogen to kill at least 30 1000000 people over the course of a year.[63] In a New York Times report, the Gates Foundation predicted that a modern outbreak like to the Spanish Influenza pandemic (which killed between 50 million and 100 million people) could stop up killing more 360 million people worldwide, fifty-fifty considering widespread availability of vaccines and other healthcare tools. The study cited increased globalization, rapid international air travel, and urbanization as increased reasons for concern.[64] In a March 9, 2017 interview with CNBC, onetime U.Due south. Senator Joe Lieberman, who was co-chair of the bipartisan Blue Ribbon Report Console on Biodefense, said a worldwide pandemic could finish the lives of more people than a nuclear state of war. Lieberman also expressed worry that a terrorist group similar ISIS could develop a constructed influenza strain and introduce it to the world to kill civilians.[64] In July 2017, Robert C. Hutchinson, former agent at the Department of Homeland Security, called for a "whole-of-government" response to the adjacent global health threat, which he described as including strict security procedures at our borders and proper execution of government preparedness plans.[64]

Also, novel approaches in biotechnology, such as synthetic biology, could be used in the future to design new types of biological warfare agents.[65] [66] [67] Special attention has to be laid on future experiments (of concern) that:[68]

  1. Would demonstrate how to render a vaccine ineffective;
  2. Would confer resistance to therapeutically useful antibiotics or antiviral agents;
  3. Would enhance the virulence of a pathogen or render a nonpathogen virulent;
  4. Would increase transmissibility of a pathogen;
  5. Would alter the host range of a pathogen;
  6. Would enable the evasion of diagnostic/detection tools;
  7. Would enable the weaponization of a biological amanuensis or toxin

Well-nigh of the biosecurity concerns in synthetic biological science, nonetheless, are focused on the function of DNA synthesis and the risk of producing genetic material of lethal viruses (due east.g. 1918 Castilian flu, polio) in the lab.[69] [seventy] [71] The CRISPR/Cas system has emerged as a promising technique for factor editing. Information technology was hailed by The Washington Post as "the almost important innovation in the synthetic biology infinite in nearly xxx years."[72] While other methods take months or years to edit gene sequences, CRISPR speeds that time up to weeks.[72] However, due to its ease of use and accessibility, it has raised a number of ethical concerns, peculiarly surrounding its employ in the biohacking infinite.[73] [74] [75]

Biosurveillance [edit]

In 1999, the Academy of Pittsburgh'south Center for Biomedical Informatics deployed the start automated bioterrorism detection system, called RODS (Real-Time Outbreak Illness Surveillance). RODS is designed to collect data from many data sources and utilize them to perform signal detection, that is, to detect a possible bioterrorism event at the earliest possible moment. RODS, and other systems like it, collect data from sources including clinic information, laboratory information, and data from over-the-counter drug sales.[72] [76] In 2000, Michael Wagner, the codirector of the RODS laboratory, and Ron Aryel, a subcontractor, conceived the thought of obtaining live data feeds from "non-traditional" (not-health-intendance) data sources. The RODS laboratory'south first efforts eventually led to the institution of the National Retail Data Monitor, a organisation which collects data from 20,000 retail locations nationwide.[72]

On Feb v, 2002, George West. Bush visited the RODS laboratory and used it as a model for a $300 one thousand thousand spending proposal to equip all 50 states with biosurveillance systems. In a voice communication delivered at the nearby Masonic temple, Bush compared the RODS system to a modernistic "DEW" line (referring to the Common cold State of war ballistic missile early warning arrangement).[77]

The principles and practices of biosurveillance, a new interdisciplinary science, were defined and described in the Handbook of Biosurveillance, edited past Michael Wagner, Andrew Moore and Ron Aryel, and published in 2006. Biosurveillance is the science of real-time illness outbreak detection. Its principles utilise to both natural and homo-made epidemics (bioterrorism).

Information which potentially could assist in early on detection of a bioterrorism event include many categories of data. Health-related information such as that from hospital computer systems, clinical laboratories, electronic health tape systems, medical examiner record-keeping systems, 911 call middle computers, and veterinary medical record systems could be of help; researchers are also considering the utility of data generated by ranching and feedlot operations, food processors, drinking water systems, school attendance recording, and physiologic monitors, among others.[76]

In Europe, affliction surveillance is starting time to be organized on the continent-wide scale needed to track a biological emergency. The arrangement non only monitors infected persons, but attempts to discern the origin of the outbreak.

Researchers accept experimented with devices to detect the existence of a threat:

  • Tiny electronic chips that would incorporate living nervus cells to warn of the presence of bacterial toxins (identification of broad range toxins)
  • Cobweb-optic tubes lined with antibodies coupled to light-emitting molecules (identification of specific pathogens, such as anthrax, botulinum, ricin)

Some enquiry shows that ultraviolet barrage photodiodes offer the high proceeds, reliability and robustness needed to find anthrax and other bioterrorism agents in the air. The fabrication methods and device characteristics were described at the 50th Electronic Materials Conference in Santa Barbara on June 25, 2008. Details of the photodiodes were also published in the Feb fourteen, 2008 issue of the journal Electronics Letters and the November 2007 issue of the journal IEEE Photonics Applied science Letters.[78]

The United States Section of Defence conducts global biosurveillance through several programs, including the Global Emerging Infections Surveillance and Response System.[79]

Another powerful tool developed within New York Urban center for use in countering bioterrorism is the evolution of the New York City Syndromic Surveillance Organization. This system is substantially a manner of tracking disease progression throughout New York City, and was developed past the New York City Department of Wellness and Mental Hygiene (NYC DOHMH) in the wake of the 9/eleven attacks. The organization works by tracking the symptoms of those taken into the emergency department—based on the location of the hospital to which they are taken and their home address—and assessing any patterns in symptoms. These established trends can so be observed by medical epidemiologists to make up one's mind if there are any affliction outbreaks in whatever particular locales; maps of disease prevalence can then exist created rather hands.[80] This is an obviously beneficial tool in fighting bioterrorism as it provides a means through which such attacks could exist discovered in their nascence; assuming bioterrorist attacks issue in like symptoms across the board, this strategy allows New York City to answer immediately to any bioterrorist threats that they may face with some level of alacrity.

Response to bioterrorism incident or threat [edit]

Government agencies which would be chosen on to respond to a bioterrorism incident would include law enforcement, hazardous materials and decontamination units, and emergency medical units, if available.

The US military has specialized units, which can reply to a bioterrorism consequence; among them are the United States Marine Corps' Chemic Biological Incident Response Force and the U.Southward. Ground forces's 20th Back up Command (CBRNE), which can discover, place, and neutralize threats, and decontaminate victims exposed to bioterror agents. US response would include the Centers for Affliction Control.

Historically, governments and authorities accept relied on quarantines to protect their populations. International bodies such as the World Health Organization already devote some of their resources to monitoring epidemics and accept served immigration-house roles in historical epidemics.

Media attention toward the seriousness of biological attacks increased in 2013 to 2014. In July 2013, Forbes published an article with the title "Bioterrorism: A Dirty Picayune Threat With Huge Potential Consequences."[81] In November 2013, Play tricks News reported on a new strain of botulism, saying that the Centers for Disease and Command lists botulism as one of two agents that accept "the highest risks of mortality and morbidity", noting that there is no antidote for botulism.[82] USA Today reported that the U.Due south. war machine in November was trying to develop a vaccine for troops from the bacteria that crusade the disease Q fever, an agent the military in one case used as a biological weapon.[83] In Feb 2014, the erstwhile special assistant and senior manager for biodefense policy to President George W. Bush called the bioterrorism risk imminent and uncertain[84] and Congressman Nib Pascrell chosen for increasing federal measures against bioterrorism every bit a "affair of life or death."[85] The New York Times wrote a story saying the United States would spend $xl million to help certain depression and eye-income countries deal with the threats of bioterrorism and infectious diseases.[86]

Nib Gates has warned that bioterrorism could impale more than people than nuclear state of war.[87]

In February 2018, a CNN employee discovered on an aeroplane a "sensitive, top-underground document in the seatback pouch explaining how the Section of Homeland Security would respond to a bioterrorism attack at the Super Bowl."[88]

2017 U.Due south. budget proposal affecting bioterrorism programs [edit]

President Donald Trump promoted his first upkeep around keeping America safe. However, one aspect of defense would receive less money: "protecting the nation from deadly pathogens, man-made or natural," according to The New York Times. Agencies tasked with biosecurity get a decrease in funding under the Administration'due south upkeep proposal.[89]

For instance:[89]

  • The Role of Public Wellness Preparedness and Response would exist cut by $136 million, or 9.vii percentage. The office tracks outbreaks of disease.
  • The National Middle for Emerging and Zoonotic Infectious Diseases would be cutting by $65 meg, or 11 per centum. The center is a co-operative of the Centers for Illness Control and Prevention that fights threats similar anthrax and the Ebola virus, and additionally towards research on HIV/AIDS vaccines.
  • Within the National Institutes of Health, the National Constitute of Allergy and Infectious Diseases (NIAID) would lose 18 percent of its budget. NIAID oversees responses to Zika, Ebola and HIV/AIDS vaccine research.

"The adjacent weapon of mass destruction may not exist a bomb," Lawrence O. Gostin, the managing director of the Earth Health System'southward Collaborating Middle on Public Health Law and Human Rights, told The New York Times. "Information technology may be a tiny pathogen that you tin't come across, smell or sense of taste, and by the time we discover it, information technology'll be too late."[89]

Lack of international standards on public health experiments [edit]

Tom Inglesy, the CEO and director of the Centre for Wellness Security at the Johns Hopkins Bloomberg School of Public Wellness and an internationally recognized expert on public health preparedness, pandemic and emerging infectious disease said in 2017 that the lack of an internationally standardized approval process that could be used to guide countries in conducting public health experiments for resurrecting a disease that has already been eradicated increases the gamble that the disease could exist used in bioterrorism. This was in reference to the lab synthesis of horsepox in 2017 past researchers at the Academy of Alberta. The researchers recreated horsepox, an extinct cousin of the smallpox virus, in society to research new means to treat cancer.[90]

In pop civilization [edit]

Incidents [edit]

Date Incident Organism Details Sources
1984 Rajneeshee religious cult attacks, The Dalles, Oregon Salmonella typhimurium Contaminated restaurant salad bars, hoping to incapacitate the population so their candidates would win the county elections

751 illnesses, Early investigation by CDC suggested the event was a naturally occurring outbreak. Cult member arrested on unrelated charge confessed involvement with the upshot

1990s Aum Shinrikyo attempts in Tokyo, Japan

Tokyo subway sarin assail, Matsumoto incident

Bacillus anthracis, Clostridium botulinum Broadcasting: Aerosolization in Tokyo

Shoko Asahara was bedevilled of criminal activity Aum Shinrikyo ordered C. botulinum from a pharmaceutical company and attempted to larn Ebola from Zaire outbreak under guise of a "humanitarian mission" Resulted in around 20 deaths and more than 4000 injuries

2001 "Amerithrax" Bacillus anthracis Letters containing anthrax spores were mailed to media offices and senators

Suspected perpetrator was a US DOD scientist

22 infected, 5 deaths

1995 Larry Wayne Harris, a white supremacist, ordered 3 vials of Yersinia pestis from the ATCC Yersinia pestis
2003 Thomas C. Butler, U.s.a. professor Yersinia pestis thirty vials of Y. pestis missing from lab (never recovered); Butler served nineteen months in jail
1987-1990 David J. Acer, Florida dentist HIV Infected 6 patients after he was diagnosed with HIV
1998 Richard J. Schmidt, a gastroenterologist in Louisiana HIV Convicted of attempted 2nd degree murder for infecting nurse Janice Allen with HIV by injecting her with blood from an AIDS patient
1999 Brian T. Stewart, a phlebotomist HIV Sentenced to life in prison for deliberately infecting his xi-month-quondam baby with HIV-infected blood to avoid child back up payments
1964-1966 Dr. Mitsuru Suzuki, doctor with grooming, Nihon Shigella dysenteriae and Salmonella typhi Objective: Revenge due to deep antagonism to what he perceived equally a prevailing seniority system

Dissemination: Sponge cake, other food sources Official investigation started afterwards anonymous tip to Ministry of Health and Welfare. He was charged, but was not convicted of whatever deaths; later implicated in 200 – 400 illnesses and 4 deaths

1996 Diane Thompson, clinical laboratory technician, Dallas, TX Shigella dysenteriae Blazon 2 Removed Shigella dysenteriae Type 2 from hospital'due south drove and infected co-workers with contaminated pastries in the role breakroom

Infected 12 of her coworkers, she was arrested, convicted, & sentenced to 20 years in prison house

See also [edit]

  • Biodefence
  • Biological Weapons Convention
  • Biorisk
  • Biosecurity
  • Project Bacchus
  • Select agent

References [edit]

  1. ^ a b c d eastward Croddy, Eric; Perez-Armendariz, Clarissa; Hart, John (2002). Chemical and biological warfare : a comprehensive survey for the concerned citizen. Copernicus Books. pp. 78-84. ISBN0387950761.
  2. ^ Roberge, Lawrence F. (2019). "Agrobioterrorism". Defense Against Biological Attacks. pp. 359–383. doi:10.1007/978-iii-030-03071-1_16. ISBN978-3-030-03070-4. S2CID 239249186.
  3. ^ "Bioterrorism | Anthrax | CDC". www.cdc.gov . Retrieved 25 Oct 2017.
  4. ^ "Bioterrorism Overview". Centers for Illness Control and Prevention. 2008-02-12. Archived from the original on 2016-03-03. Retrieved 2009-05-22 .
  5. ^ Preston, Richard (2002). The Demon in the Freezer, Ballantine Books, New York. ISBN 9780345466631.
  6. ^ Advantages of Biologics as Weapons Bioterrorism: A Threat to National Security or Public Health Defining Issue? MM&I 554 University of Wisconsin–Madison and Wisconsin Land Laboratory of Hygiene, September xxx, 2008.
  7. ^ Joy, Bill (2007-03-31), Why the Time to come Doesn't Demand United states of america: How 21st Century Technologies Threaten to Make Humans an Endangered Species, Random House, ISBN978-0-553-52835-0
  8. ^ "Bioterrorism - the high economical costs of an attack" (PDF). October 2002.
  9. ^ a b Gregory, B; Waag, D. (1997), Military Medicine: Medical aspects of biological warfare (PDF), Part of the Surgeon General, Department of the Army, Library of Congress 97-22242, archived from the original (PDF) on 2009-06-12, retrieved 2009-05-22
  10. ^ Experts Q & A, Public Dissemination Service, 2006-12-fifteen, archived from the original on 2009-05-20, retrieved 2009-05-22
  11. ^ West. Seth Carus, "R.I.S.E.", in Toxic Terror: Assessing Terrorist Use of Chemic and Biological Weapons (MIT Press, 2000), p.55, p.69
  12. ^ By U.S. Incidents of Food Bioterrorism. In Bioterrorism: A Threat to National Security or Public Health Defining Result, University of Wisconsin–Madison and the Wisconsin State Laboratory of Hygiene, MM&I 554, September 30, 2008 [ permanent dead link ]
  13. ^ Novak, Matt (2016-11-03). "The Largest Bioterrorism Attack In US History Was An Attempt To Swing An Election". Gizmodo . Retrieved 2016-12-02 .
  14. ^ a b "CDC-Bacillus anthracis Incident, Kameido, Tokyo, 1993". Archived from the original on 2020-02-02. Retrieved 2016-10-06 .
  15. ^ CNN
  16. ^ Petersen, Carolyn (May 1995). "Cryptosporidium and the nutrient supply". The Lancet. 345 (8958): 1128–1129. doi:x.1016/s0140-6736(95)90972-9. PMID 7723540. S2CID 26919903.
  17. ^ Lathrop, Peggy; Isle of mann, Linda M. (2001). "Preparing for bioterrorism". Proceedings (Baylor University. Medical Eye). fourteen (iii): 219–223. doi:10.1080/08998280.2001.11927766. PMC1305820. PMID 16369620.
  18. ^ a b Wheelis, Marker; Casagrande, Rocco; Madden, Laurence Five. (one July 2002). "Biological Attack on Agriculture: Low-Tech, High-Affect BioterrorismBecause bioterrorist attack requires relatively petty specialized expertise and engineering science, it is a serious threat to US agronomics and can take very large economic repercussions". BioScience. 52 (7): 569–576. doi:ten.1641/0006-3568(2002)052[0569:BAOALT]2.0.CO;ii.
  19. ^ Weber, Stephen M; Bottei, Ed; Melt, Richard; O'Connor, Michael (Baronial 2004). "SARS, emerging infections, and bioterrorism preparedness". The Lancet. Infectious Diseases. 4 (8): 483–484. doi:10.1016/S1473-3099(04)01098-9. PMC7128359. PMID 15288816.
  20. ^ Cook, Alethia H.; Cohen, David B. (September 2008). "Pandemic Disease: A Past and Future Challenge to Governance in the U.s.a.". Review of Policy Research. 25 (5): 449–471. doi:10.1111/j.1541-1338.2008.00346.10. PMC7169208. PMID 32327945.
  21. ^ Cook, Alethia H.; Cohen, David B. (September 2008). "Pandemic Affliction: A Past and Time to come Challenge to Governance in the Us". The Review of Policy Research. 25 (5): 449–471. doi:10.1111/j.1541-1338.2008.00346.x. PMC7169208. PMID 32327945.
  22. ^ Function of the President. White Business firm. (1 Nov 2005). "Press release: President outlines pandemic flu preparations and response."
  23. ^ "CDC Tularemia - Emergency Preparedness & Response". 2019-02-21.
  24. ^ "CDC Tularemia - Central Facts About Tularemia". Archived from the original on 2010-06-xix.
  25. ^ Adalja, Amesh A.; Toner, Eric; Inglesby, Thomas V. (2015-03-05). "Clinical Management of Potential Bioterrorism-Related Weather condition". New England Journal of Medicine. 372 (10): 954–962. doi:ten.1056/NEJMra1409755. PMID 25738671.
  26. ^ Vietri, Nicholas J.; Purcell, Bret Chiliad.; Tobery, Steven A.; Rasmussen, Suzanne L.; Leffel, Elizabeth K.; Twenhafel, Nancy A.; Ivins, Bruce E.; Kellogg, Mark D.; Webster, Wendy One thousand.; Wright, Mary E.; Friedlander, Arthur Grand. (2009). "A Brusque Course of Antibiotic Handling Is Effective in Preventing Expiry from Experimental Inhalational Anthrax afterward Discontinuing Antibiotics". The Journal of Infectious Diseases. 199 (iii): 336–41. doi:10.1086/596063. JSTOR 40254424. PMID 19099484.
  27. ^ Bisher, Jamie, "During World War I, Terrorists Schemed to Use Anthrax in the Cause of Finnish Independence," Military History, Baronial 2003, pp. 17–22.Anthrax Demolition in Republic of finland
  28. ^ "Emerging Infectious Diseases journal". Archived from the original on 2010-10-15. Retrieved 2017-09-08 .
  29. ^ Clarke, S. C. (2005). "Leaner as potential tools in bioterrorism, with an emphasis on bacterial toxins". British Periodical of Biomedical Science. 62 (i): 40–46. doi:x.1080/09674845.2005.11732685. PMID 15816214. S2CID 19601885.
  30. ^ Debora MacKenzie. "Anthrax attack bug 'identical' to army strain". New Scientist . Retrieved xvi February 2013.
  31. ^ "CDC Smallpox Home". 2019-02-nineteen.
  32. ^ "CDC Smallpox - What CDC Is Doing to Protect the Public From Smallpox". Archived from the original on 2018-05-04. Retrieved 2018-12-18 .
  33. ^ "IHB - The DoD Immunization Data and Preparation Portal". Archived from the original on 2009-08-14. Retrieved 2009-05-26 .
  34. ^ "CDC Botulism - Emergency Preparedness & Response". 2019-08-nineteen.
  35. ^ Nigam, PK; Nigam, A (2010). "BOTULINUM TOXIN". Indian Periodical of Dermatology. 55 (1): viii–14. doi:10.4103/0019-5154.60343. PMC2856357. PMID 20418969.
  36. ^ "CDC - Facts Well-nigh Botulism". Archived from the original on 2017-07-03. Retrieved 2018-12-18 .
  37. ^ "CDC Plague Information - Emergency Preparedness & Response". 2019-02-21.
  38. ^ "CDC - 01 This Page Has Moved - CDC Plague Dwelling Page - CDC Division of Vector-Borne Infectious Diseases (DVBID)". Archived from the original on 2009-05-nineteen.
  39. ^ "CDC Plague - Frequently Asked Questions (FAQ) About Plague". Archived from the original on 2009-05-28.
  40. ^ "CDC Viral Hemorrhagic Fevers - Emergency Preparedness & Response". 2019-05-16.
  41. ^ Olson, Kyle B. (1999-08-04). "Aum Shinrikyo: Once and Time to come Threat?". Emerging Infectious Diseases. v (iv): 413–416. doi:10.3201/eid0504.990409. PMC2627754. PMID 10458955. Archived from the original on 2020-03-20. Retrieved 2020-02-08 .
  42. ^ "CDC Brucellosis - Emergency Preparedness & Response". 2019-05-xvi.
  43. ^ "CDC Glanders". Archived from the original on 2010-02-09. Retrieved 2017-09-08 .
  44. ^ "CDC Melioidosis". Archived from the original on 2010-02-eleven. Retrieved 2017-09-08 .
  45. ^ "CDC Why has melioidosis get a current issue?". Archived from the original on 2010-02-xi. Retrieved 2017-09-08 .
  46. ^ "CDC Q Fever - Emergency Preparedness and Response". 2019-01-15.
  47. ^ "CDC Ricin - Emergency Preparedness & Response". 2019-05-16.
  48. ^ "Cholera". WebMD.
  49. ^ Kuntz, Carol; Salerno, Reynolds; Jacobs, Eli (2013-05-xv). A Biological Threat Prevention Strategy: Complicating Adversary Acquisition and Misuse of Biological Agents. Center for Strategic & International Studies. ISBN978-1-4422-2474-2.
  50. ^ Nikolelis, Dimitrios P.; Nikoleli, Georgia-Paraskevi (2016-03-12). Biosensors for Security and Bioterrorism Applications. Springer. ISBN978-3-319-28926-7.
  51. ^ Bernett, Brian C. (Dec 2006), U.s. Biodefense and Homeland Security: Toward Detection and Attribution (PDF), Monterey, California, United states of america: Naval Postgraduate Schoolhouse, p. 21, archived from the original (PDF) on 2008-02-29, retrieved 2009-05-24
  52. ^ a b c d United States. Cong. House. Committee on Homeland Security. Ensuring Constructive Preparedness Responses and Recovery for Events Impacting Health Security Hearing before the Subcommittee on Emergency Preparedness, Response and Communications of the Commission on Homeland Security, House of Representatives, 1 Hundred Twelfth Congress, Starting time Session, March 17, 2011. 112th Cong., 1st sess. Hr 397. Washington: U.S. G.P.O., 2012. Print.
  53. ^ a b United states of america. Cong. House. Commission on Homeland Security. First Responder Technologies: Ensuring a Prioritized Approach for Homeland Security Enquiry and Development : Joint Hearing before the Subcommittee on Emergency Preparedness, Response and Communications and the Subcommittee on Cybersecurity, Infrastructure Protection, and Security Technologies of the Committee on Homeland Security, House of Representatives, One Hundred 12th Congress, Second Session, May 9, 2012. 112th Cong., 2nd sess. Hour 397. N.p.: n.p., due north.d. Impress.
  54. ^ "WKTV.com | A new Claiming for police and EMS personnel". 2016-09-15. Archived from the original on 2016-x-05. Retrieved 2016-10-03 .
  55. ^ a b c "First responders train with new technology at N.Y.'s largest emergency response exercise - Homeland Preparedness News". 2016-09-nineteen. Retrieved 2016-10-03 .
  56. ^ "Watch NY police railroad train for terrorist attacks, bombs, active shooters (videos)". 2016-09-15. Retrieved 2016-10-03 .
  57. ^ a b Hylton, Wil South. "How Gear up Are Nosotros for Bioterrorism?" The New York Times. The New York Times Visitor, 26 Oct. 2011. Web.
  58. ^ a b The states. Cong. House. Committee on Homeland Security. Taking Mensurate of Countermeasures. Hearing before the Subcommittee on Emergency Preparedness, Response and Communications of the Commission on Homeland Security, House of Representatives, One Hundred Twelfth Congress, Kickoff Session, Apr thirteen, 2011 and May 12, 2011. 112 Cong., 1st sess. 60 minutes 397. Washington: U.South. G.P.O., 2012. Impress.
  59. ^ John King, USA. CNNW. San Francisco. 20 Dec. 2011. Television.
  60. ^ MSNBC News Live. MSNBC. New York Metropolis. 26 Jan. 2010. Television set
  61. ^ a b Rozens, Tracy (2016-09-02). "RAND's Gerstein: U.South. needs biodefense strategy to protect against terror threats". Homeland Preparedness News . Retrieved 2016-09-19 .
  62. ^ McCormick, Ty. "Foiled Republic of kenya Anthrax Plot Hints At Islamic State's Scramble For Africa". Foreign Policy . Retrieved 2020-ten-19 .
  63. ^ Foundation, Neb Gates, Nib & Melinda Gates. "Nib GATES: A new kind of terrorism could wipe out xxx million people in less than a yr — and we are non prepared". Business organisation Insider . Retrieved 2020-10-19 .
  64. ^ a b c Hutchinson, Robert C. (2017-07-09). "Homeland Security Today: Sectional: Pandemic Crossroads". www.hstoday.u.s.a. . Retrieved 2017-09-12 . [ expressionless link ]
  65. ^ Kelle, Alexander (2009). "Security Issues Related to Constructed Biology". Constructed Biology. pp. 101–119. doi:x.1007/978-90-481-2678-1_7. ISBN978-ninety-481-2677-4.
  66. ^ "JCVI: Research / Projects / Constructed Genomics | Options for Governance / Overview". world wide web.jcvi.org. Archived from the original on 2016-01-30. Retrieved 2016-01-24 .
  67. ^ K.Buller, The potential use of genetic applied science to enhance orthopox viruses as bioweapons. Presentation at the International Conference 'Smallpox Biosecurity. Preventing the Unthinkable' (21–22 Oct 2003) Geneva, Switzerland
  68. ^ Kelle A. 2007. Synthetic Biology & Biosecurity Awareness In Europe. Bradford Science and Technology Study No.9
  69. ^ Tumpey, T. M.; Basler, CF; Aguilar, PV; Zeng, H; Solórzano, A; Swayne, DE; Cox, NJ; Katz, JM; Taubenberger, JK; Palese, P; García-Sastre, A (2005-10-07). "Characterization of the Reconstructed 1918 Spanish Influenza Pandemic Virus". Science. 310 (5745): 77–80. Bibcode:2005Sci...310...77T. doi:x.1126/scientific discipline.1119392. PMID 16210530. S2CID 14773861.
  70. ^ Cello, J.; Paul, A. 5.; Wimmer, E. (2002). "Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absenteeism of natural template". Science. 297 (5583): 1016–1018. Bibcode:2002Sci...297.1016C. doi:10.1126/science.1072266. PMID 12114528. S2CID 5810309.
  71. ^ Wimmer, Eckard; Mueller, Steffen; Tumpey, Terrence K; Taubenberger, Jeffery K (2009-12-01). "Constructed viruses: a new opportunity to sympathise and foreclose viral disease". Nature Biotechnology. 27 (12): 1163–72. doi:10.1038/nbt.1593. PMC2819212. PMID 20010599.
  72. ^ a b c d Wagner, Michael Yard.; Espino, Jeremy; et al. (2004), "The part of clinical information systems in public wellness surveillance", Healthcare Data Management Systems (three ed.), New York: Springer-Verlag, pp. 513–539
  73. ^ Kahn, Jennifer (2015-11-09). "The Crispr Quandary". The New York Times . Retrieved 2016-01-24 .
  74. ^ Ledford, Heidi (2015-06-01). "CRISPR, the disruptor". Nature. 522 (7554): 20–24. Bibcode:2015Natur.522...20L. doi:10.1038/522020a. PMID 26040877. S2CID 4456595.
  75. ^ Basulto, Dominic (2015-eleven-04). "Everything yous need to know about why CRISPR is such a hot technology". The Washington Post . Retrieved 2016-01-24 .
  76. ^ a b Wagner, Michael M.; Aryel, Ron; et al. (2001-11-28), Availability and Comparative Value of Data Elements Required for an Effective Bioterrorism Detection Arrangement (PDF), Real-time Outbreak and Illness Surveillance Laboratory, archived from the original (PDF) on 2011-03-03, retrieved 2009-05-22
  77. ^ Togyer, Jason (June 2002), Pitt Magazine: Airborne Defense, Academy of Pittsburgh, archived from the original on 2010-06-sixteen, retrieved 2009-05-22
  78. ^ Avalanche Photodiodes Target Bioterrorism Agents Newswise, Retrieved on June 25, 2008.
  79. ^ Pellerin, Cheryl. "Global Nature of Terrorism Drives Biosurveillance." Archived January 12, 2013, at the Wayback Machine American Forces Press Service, 27 October 2011.
  80. ^ Chen, H, D Zeng, and Y Pan. "Infectious Disease Informatics: Syndromic Surveillance for Public Health and Bio-Defense." 20120, XXII, 209p. 68 illus.., Hardcover.
  81. ^ Bell, Larry. "Bioterrorism: A Dirty Little Threat With Huge Potential Consequences". Forbes. 2013-07-21 (Retrieved 2014-02-17)
  82. ^ Heitz, David. "Deadly bioterror threats: 6 existent risks". Fox News. 2013-eleven-02 (Retrieved 2014-02-17)
  83. ^ Locker, Ray. "Pentagon seeking vaccine for bioterror illness threat". USA Today. 2013-11-eighteen (Retrieved 2014-02-17)
  84. ^ Cohen, Bryan. "Kadlec says biological attack is uncertain, imminent reality" Archived 2015-02-09 at the Wayback Machine. Bio Prep Watch. 2014-02-17 (Retrieved 2014-02-17)
  85. ^ Cohen, Bryan. "Pascrell: Bioterror threat a life or death affair". Bio Prep Lookout. 2014-02-12 (Retrieved 2014-02-17)
  86. ^ Tavernise, Sabrina. "U.Due south. Backs New Global Initiative Against Infectious Diseases". New York Times. 2014-02-13 (Retrieved 2014-02-17)
  87. ^ "Bioterrorism could impale more people than nuclear war, Pecker Gates to warn world leaders". The Telegraph. 18 February 2017. Archived from the original on 2022-01-12. Retrieved 19 February 2017.
  88. ^ Evensen, Jay (2018-02-12). "Jay'due south Jokes: Did you forget your bioterrorism study on the plane?". DeseretNews.com . Retrieved 2018-02-xvi .
  89. ^ a b c Baumgaertner, Emily (2017-05-28). "Trump'due south Proposed Budget Cuts Problem Bioterrorism Experts". The New York Times. Archived from the original on 2022-01-01. Retrieved 2017-05-30 .
  90. ^ Riley, Kim (2017-08-10). "Bioterrorism threats crave common global experimentation oversight, expert says". Homeland Preparedness News . Retrieved 2018-01-15 .

Bibliography [edit]

  • Cake, Steven K. (2001), "The growing threat of biological weapons", American Scientist, 89 (1): 28, Bibcode:2001AmSci..89.....B, doi:10.1511/2001.ane.28, retrieved 2009-05-22
  • Christopher, G. Westward.; et al. (1998), Adapted from Biological Warfare: A Historical Perspective, Fort Detrick, Maryland: Operational Medicine Sectionalization
  • Eitzen, Eastward.; Takafuji, Due east. (1997), "Historical Overview of Biological Warfare", Military machine Medicine: Medical Aspects of Chemic and Biological Warfare, Part of the Surgeon General, Section of the Army
  • Republic of iraq's Biological Weapon Plan, Iraq'southward Biological Weapon Program, August 2006, archived from the original on 2009-04-11, retrieved 2009-05-22
  • Milanovich, F. (June 1998), Reducing the threat of biological weapons, Scientific discipline and Technology Review, pp. 4–9, archived from the original on 2008-11-23, retrieved 2009-05-22
  • Paquette, Laure (2006-06-29), Bioterrorism in Medical and Healthcare Administration (i ed.), CRC, ISBN978-0-8247-5651-2 , retrieved 2009-05-22
  • Wagner, M.; Moore, A.; Aryel, R. (2006), Handbook of Biosurveillance, San Diego, California, United states of america: Bookish Press

Further reading [edit]

  • "1540 Committee (Security Quango Committee established pursuant to resolution 1540 (2004)): 1540 Fact Canvas". Un. 28 April 2004. Resolution 1540 "affirms that the proliferation of nuclear, chemical and biological weapons and their ways of delivery constitutes a threat to international peace and security. The resolution obliges States, inter alia, to refrain from supporting by any means non-State actors from developing, acquiring, manufacturing, possessing, transporting, transferring or using nuclear, chemical or biological weapons and their ways of delivery".
  • NOVA: Bioterror
  • Carus, W. Seth Working Paper: Bioterrorism and Biocrimes. The Illicit Employ of Biological Agents Since 1900, February 2001 revision. (Final published version: Seth Carus, W. (2002). Working Paper: Bioterrorism and Biocrimes. The Illicit Apply of Biological Agents Since 1900 (8th ed.). ISBN9781410100238. OCLC 51843844. )

United States [edit]

  • "Public Health Security and Bioterrorism Preparedness and Response Act of 2002: An Act to improve the ability of the United States to prevent, prepare for, and reply to bioterrorism and other public health emergencies (H.R. 3448)" (PDF). Public Police 107–188107th Congress. 12 June 2002.
  • Recommended Policy Guidance for Departmental Evolution of Review Mechanisms for Potential Pandemic Pathogen Care and Oversight (P3CO). Obama Assistants. January 9, 2017.

Source: https://en.wikipedia.org/wiki/Bioterrorism

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